Alienated in politically-ambiguous Moscow, a young woman deals with severe OCD, while her cousin in Berlin tries to build a romantic relationship ignoring her own condition. In a parallel New York City realm, a heartbroken boxer struggles with addiction, self worth and online anxiety, which connects all the characters on a universal level.

Down and out private-eye Jimmy Baz reluctantly takes on a case to find a missing college student when dead bodies of Muslim men start turning up leading him to believe he is now searching for a serial killer.

An affluent African American psychiatrist is sent to federal prison after being found guilty of murdering his wife, then sent to solitary confinement - a victim of systemic racism. Isolated and fighting for an appeal, he slowly descends into madness, pushed to his breaking point by an abusive female guard hell bent on her own form of justice. Haunted by internal demons and his dead wife, he questions his own innocence and sanity, making his time in the S.H.U. a never-ending nightmare.